C-C motif chemokine 18 (Protein name
), CCL18_HUMAN from NCBI database.
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Gene name:
CCL18(AMAC1;DCCK1;MIP4;PARC;SCYA18);
Protein name:
C-C motif chemokine 18;
Alternative:
CC chemokine PARC;Alternative macrophage activation-associated CC chemokine 1(AMAC-1);Macrophage inflammatory protein 4(MIP-4);Dendritic cell chemokine 1(DC-CK1);Small-inducible cytokine A18;Pulmonary and activation-regulated chemokine;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
N/A
Function:
Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.
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Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
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Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF N-TERMINUS
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Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];CHARACTERIZATION
7.
"The genomic locus for the AMAC-1 gene contains possible pseudo-exons within the first intron sequence." Politz O.
,
Kodelja V.
,
Guillot P.
,
Orfanos C.E.
,
Goerdt S.
Submitted (1998-12) to the EMBL/GenBank/DDBJ databases
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Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
8.
"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)." Ebert L.
,
Schick M.
,
Neubert P.
,
Schatten R.
,
Henze S.
,
Korn B.
Submitted (2004-05) to the EMBL/GenBank/DDBJ databases
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Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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Cited for: IDENTIFICATION OF CCL18(3-69) AND CCL18(4-69);PROTEOLYTIC PROCESSING OF N-TERMINAL;FUNCTION;MASS SPECTROMETRY;TISSUE SPECIFICITY;INDUCTION
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Cited for: IDENTIFICATION OF CCL18(1-68);PROTEOLYTIC PROCESSING OF C-TERMINAL;FUNCTION